Drug class
Immunosuppressants and cannabis
CBD is a strong CYP3A4 inhibitor. These drugs are cleared by CYP3A4 and sit inside a narrow therapeutic window.
High risk
Why it happens
CBD is a strong CYP3A4 inhibitor. These drugs are cleared by CYP3A4 and sit inside a narrow therapeutic window.
What it means for you
Trough levels can climb into toxic territory, or fall unexpectedly if cannabis is stopped.
What Tiffany advises
If you have had a transplant or take one of these for an autoimmune condition, do not start cannabis without your transplant team involved.
Common examples
Generic names first, then brands.
- tacrolimus
- cyclosporine
- sirolimus
Body systems involved
- Immune
- Diabetes and metabolism
Take it further
Check this with my other meds
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