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Drug class

Statins (cholesterol) and cannabis

CBD's effect on CYP3A4 can nudge statin blood levels up a little, and simvastatin is the most sensitive of the group.

Lower risk

Why it happens

CBD's effect on CYP3A4 can nudge statin blood levels up a little, and simvastatin is the most sensitive of the group.

What it means for you

There is a small theoretical chance of muscle aches when both doses are high.

What Tiffany advises

This pairing is generally well tolerated. Mention it to your primary care provider at your next visit.

Common examples

Generic names first, then brands.

  • atorvastatin
  • simvastatin
  • rosuvastatin

Body systems involved

  • Heart and blood pressure

Take it further

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Other classes at lower risk

This page describes a drug class from aggregate published knowledge, reviewed by a pharmacist. Your own prescriber or pharmacist knows your doses and history; bring this page to that conversation.